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Does Ice Fog Controlled Nucleation Add Water/Ice to the Product?

Researchers often ask what the difference is in controlled nucleation techniques and if ice fog added measurable ice to the product.   Tatsuhiro Kadama, PhD, from Daiichi Sankyo Parenteral Formulation Research Group and studying at Purdue University, took on this project.  With the help of Dr. Alina Alexeenko, a high quality/resolution balance was borrowed, and ice fog controlled nucleation was studied.  The method and conclusions for this study are posted in the LyoSights section of the Millrock website and can be seen HERE along with other articles of interest for freeze drying scientists.