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Non-Sterile Production Freeze Dryers

Production Freeze Dryers/Lyophilizers

Biotech and Industrial applications can vary greatly. Pharmaceutical lyophilizers typically require sterilization (SIP) between each cycle. However, Industrial Freeze Dryer applications often do not require sterilization. To accommodate the large range of requirements between each industry, Millrock Technology offers Non-Sterile Freeze Dryers in the following specifications:


  • 304L stainless steel for non-pharmaceutical applications.
  • 316L stainless steel for pharmaceutical applications.

Custom Designed to Fit Your Needs

Our lyophilizers can be custom designed to fit your application needs. Our condenser assemblies can be internal or external with the option of either bulk or stoppering style shelf assemblies. Cylindrical chambers are another option that offer cost savings and can be supplied up to 80 square feet in shelf area. Additionally, options such as: isolation valves, redundant compressors, redundant vacuum pumps, and clean-in-place (CIP) piping can also be provided.

Typical Operations Specifications for Non-Sterile Freeze Dryers

Condenser Cool Down< 10 minutes to –50 C
Defrost Time< 30 minutes
Ultimate Vacuum5 mT
Vacuum Pull-Down< 20 minutes to 100 mT
Vacuum Leak Rate< 3 x 10-2 mbar-liter/sec
Shelf Cooling (20 C to –40C)<40 minutes
Shelf Heating> 1 C/min

Non-Sterile Freeze Dryers Features

Control System PLC Opto 22 or Allen-Bradley
Shelf Temperature Range -60C to +65C (+80C option)
Shelf Heat Transfer Hollow Fluid Filled
Shelf Material and Finish 316L, 20 Ra or better with Optional Electropolish
Shelf Area 8 sq ft to 10 sq ft
Shelf Assembly Bulk or Hydraulic Stoppering
Condenser Temperature -75 C
Chamber Configuration Cylindrical or Rectangular
Chamber Rating Full Vacuum
Condenser Style Coil or Plate
Compressors Two StageCarlyle, Bitzer, Mycom (screw)
Defrost Hot Gas or Hot Water
Vacuum Pump Leybold Rotary Vane or Dry Pumps
Vacuum Control Pirani
with Solenoid & Needle Valve
Gas Backfill Included
Product Sensors One per shelf standard
Water Ring Pump Nash-Elmo
Frame Welded and Painted

For a complete list and comparison of all our Freeze Dryers, please visit our main Freeze Dryer page.